ASUS Prime TRX40-Pro S is expertly engineered to unleash the full potential of AMD's latest high-core-count processors for content creators, designers and professional use. Combining a robust power design, comprehensive cooling solutions, ultrafast PCIe 4.0 connectivity and intelligent tuning options, the high-end desktop motherboard delivers the performance and stability needed to turn every creative vision into reality.
- AMD Socket sTRX4: Ready for the latest 3rd Gen AMD Ryzen™ Threadripper™ series processors (support up to 64 cores)
- Robust power design: 16 power stages, ProCool II connectors with solid pins, and premium chokes and capacitors for stable power delivery
- Comprehensive thermal solutions: VRM heatsink, M.2 heatsink, SoC VRM heatsink, active chipset heatsink solution, and an array of hybrid fan headers
- Next-gen connectivity: Three PCIe 4.0 NVMe M.2 slots, USB 3.2 Gen 2 Type-C™ front-panel connector, and Intel Gigabit Ethernet
- Intelligent tuning: ASUS 5-Way Optimization software and renowned UEFI BIOS offer easy configuration options for all experience levels
6 x USB 3.2 Gen 1
BIOS FlashBack™ Button
4 x USB 3.2 Gen 2
(3 x Type-A & 1 x Type-C™)
Intel® Gb Ethernet
8-Channel HD Audio
3 x PCIe 4.0 (x16/x16/x16)
● 2-Way SLI & 2-Way CFX Support
● ASUS SafeSlot
Crystal Sound 3
● Realtek® S1220 Codec
● Power Pre-Regulator
● De-Pop Circuit
● Audio Shielding
● Premium Japanese
● Dedicated Audio
● DTS:X® Ultra
2 x 8-Pin ProCool II Connectors
16 Power Stages
4-Pin RGB Header
Addressable Gen 2 RGB Header
DDR4 4666+ (O.C.)
AMD Socket sTRX4 for 3rd Gen
AMD Ryzen™ Threadripper™
Vertical M.2 22110
(PCIe 4.0 x4 & SATA Modes)
USB 3.2 Gen 2 Type-C™
AMD TRX40 Chipset
2 x M.2 22110
(PCIe 4.0 x4 Mode)
8 x SATA 6Gb/s
Addressable Gen 2 RGB Header
4-Pin RGB Header
Get the Most out of All Your Cores
AMD's HEDT platform raises the stakes with the latest AMD 3rd Gen Ryzen™ Threadripper™ processors that boast more cores and higher bandwidth than ever before. Prime TRX40-Pro S is ready for the additional processing power that plows through intensive tasks such as 3D rendering and video editing, and the extra bandwidth allows you to add multiple graphics cards and NVMe SSDs to accelerate your productivity.
Robust Power Design
The new AMD Socket sTRX4 is compatible with 3rd Gen AMD Ryzen Threadripper CPUs with up to 64 cores, up to 64 PCIe 4.0 lanes, and 280-watt thermal design power (TDP). Such specifications require serious power, so Prime TRX40-Pro S is equipped with an enhanced power solution that includes 16 power stages to ensure your processor keeps up with your creativity.
ProCool II Connectors
ProCool II connectors ensure a snug and reliable connection to the EPS 12V power lines. The second-generation features upgrades of metal amour and solid pins for better heat dissipation, as well as a warning LED-display with a BIOS POST message to indicate improper connections.
16 Power Stages
Prime TRX40-Pro S's VRM is comprised of 16 power stages, delivering the power and efficiency that the latest AMD processors demand.
Premium Chokes and Caps
Superior chokes and durable caps are engineered to resist extreme temperatures and provide better performance.
Make Your Memory Go Faster
The TRX40 platform delivers ample bandwidth on multiple fronts. Its quad-channel memory controller supports up to 256 GB of DDR4 memory across eight slots.
CPU: AMD 3rd Gen Ryzen Threadripper 3960X | Motherboard: Prime TRX40-Pro S |
DRAM: Crucial BLE8G4D40BEEAK.M8FE1 | Water-cooling: Corsair H115i
Fully loaded takes on a new meaning when you have up to 64 PCIe 4.0 lanes stemming from the CPU. These lanes can be split in an x16/x16/x16 configuration spanning the board's trio of PCIe x16 slots, allowing you to load up on GPUs to supercharge your work efficiency – whether you're a CAD professional, 3D artist or other content creation experts.
Protect Your Graphics Card Investment
Each PCI Express slot is bolstered with reinforced walls and a stronger connection to the PCB, which helps it withstand the weight of heavier graphics coolers and protects your investment.
Triple PCIe 4.0 M.2
Serious Speed with Onboard M.2
Professional content creation applications require fast solid-state storage, which is why Prime TRX40-Pro S is equipped with three PCIe 4.0 M.2 slots that are compatible with the latest NVMe SSDs. All slots support up to 110 mm drives, and they can be configured into bootable RAID arrays for ultrafast data-transfer speeds.
USB 3.2 Gen 2 Type-C Front-Panel Connector
Plenty of USB ports are provided to support high-end rigs loaded with peripherals, including a front-panel Type-C™ connector with faster USB 3.2 Gen 2 connectivity for compatible cases.
Pumped-Up Throughput. 2.5X-Higher Surge Tolerance.
ASUS LANGuard is a hardware-level networking protection that employs signal-coupling technology and premium anti-EMI surface-mounted capacitors to ensure a more reliable connection and better throughput.
Network-Optimization Software for Customizable Packet Prioritization
Turbo LAN with cFosSpeed traffic-shaping technology allows you to configure application priority via an intuitive interface and reduces network lag.
Cool to the Core
Effective content creation demands a reliable, professional foundation. Prime TRX40-Pro S is engineered with multiple onboard heatsinks and an array of hybrid fan headers to ensure your rig stays cool and stable under intense workloads, so that your focus remains fixed on your creative goals.
Two M.2 slots are covered by a massive heatsink to combat temperature-induced throttling that can affect performance during heavy, sustained storage loads.
Removable captive screws reduce risk of drops or losses during heatsink removal
VRM Heatsink and Thermal Pads
A massive VRM heatsink and high-quality thermal pads enhance heat transfer from the MOSFETs and chokes for better cooling performance. A fan holder is bundled for additional cooling options.
SoC VRM Heatsink
Prime TRX40-Pro S features an SoC VRM heatsink, positioned in the pathway of the chipset fan's airflow, to enable the SoC VRM to stay cool during memory overclocking.
Active Chipset Heatsink Solution
Dedicated Cooling for Unthrottled Transfers
PCIe 4.0 provides twice the bandwidth for data flowing through the chipset, which creates more heat than the previous generation. Prime TRX40-Pro S features an actively cooled heatsink to prevent throttling during sustained transfers, designed with the screws on top for easy access and maintenance.
Active Chipset Heatsink Solution includes:
- Air Duct: A specially-designed air duct helps the fan generate static pressure and concentrates air flow over the fins.
- Finned Heatsink: The heatsink fin density is optimized to maximize surface area while maintaining a low-resistance exhaust path.
- Custom Delta Superflo Fan: The custom low-noise fan features a high-durability bearing with a 60,000-hour L10* lifespan, while its speed is easily adjusted via Fan Xpert 4 or the UEFI.
* L10 bearing life is a standard metric that specifies the number of hours that 90% of the bearing are expected to continue successfully operating, as a minimum.
Cooler by Design
Prime TRX40-Pro S features the most comprehensive cooling controls ever, configurable via Fan Xpert 4 or the UEFI BIOS.
- Multiple Temperature Sources
- Dual Pump Headers
- Smart Protection
- 4-Pin PWM/DC Fan
Each header can dynamically reference three thermal sensors, and via Fan Xpert 4 you can even map the temperature of supported ASUS graphics cards to optimize cooling for GPU- and CPU-intensive tasks.
A dedicated header that supplies over 3A for high-performance PWM or DC water pumps, plus a second dedicated header for AIOs.
A dedicated integrated circuit that protects each fan header from overheating and overcurrent.
Each onboard header supports auto-detection of PWM or DC fans.
Tune It Your Way
Comprehensive controls form the foundation of the ASUS Prime series. Prime TRX40-Pro S packs flexible tools to tune every aspect of your system, enabling you to tweak performance settings to perfectly match the way you work – maximizing your productivity.
One click takes care of all that complex tuning. ASUS 5-Way Optimization makes your PC smart. It dynamically optimizes essential aspects of the system, providing overclocking and cooling profiles that are tailored for your rig.
- An automated tuning utility that optimizes overclocking and cooling profiles for your unique system configuration.
- Fans stay quiet as a whisper for everyday computing, and deliver optimal airflow when the system is crunching through CPU- or GPU-intensive tasks.
- The stress test allows you to optimize and overclock for CPU- or memory-centric workloads.
CPU Performance Boost
The TurboV Processing Unit (TPU) is the intelligence behind our automated system-tuning utility, offering the ability to fine-tune voltages, monitor system stats, and adjust overclock parameters for optimal performance.
All-Around Energy Efficiency
With the Energy Processing Unit (EPU), you'll enjoy system-wide power savings. The EPU automatically optimizes power consumption and maximizes savings with the Away mode.
Flexible Cooling Controls for Air or Liquid
With Prime TRX40-Pro S, you have comprehensive control over fans via Fan Xpert 4 or UEFI. Whether you're cooling with air or water, Auto-Tuning mode intelligently configures all parameters with a single click. There's also an Extreme Quiet mode, which reduces all fan speeds to below the default minimum – keeping your system quiet as a whisper when performing light tasks.
Precise Digital Power Control
The Digi+ voltage-regulator module (VRM) delivers a real-time control over voltages, switching frequency and power-efficiency settings, allowing you to fine-tune your CPU for ultimate stability and performance.
Turbo App allows you to define CPU overclocking, apply fan profiles, prioritize network data and optimize audio setting at app level, meaning your system is perfectly optimized for what you're doing.
The renowned UEFI BIOS provides everything you need to configure, tweak, and tune your rig. It offers intelligently simplified options for newcomers to PC DIY, as well as comprehensive features for seasoned veterans.
Advanced Tuning for Serious Tweakers
When you're ready to take a deeper dive into the configuration of your rig, Advanced Mode grants total control. Each section is intuitively organized, and a built-in search feature makes it easy to find the option you need. Tweak cooling parameters, save profiles, apply overclocks, and unleash the full potential of the latest Ryzen processor.
The FlexKey offers a new option to remap the system reset button on the chassis to toggling Aura lighting on/off or boot directly into the UEFI.
Quickly and easily find the option or setting that you're looking for.
ASUS User Profile
Port configuration settings between different BIOS versions or share them with friends.
Quickly discover tuning options and add preferred tools to the list.
Quick and Simple Setup
Designed to simplify setup, EZ mode presents all the vital settings and stats on one single page. With guided wizards, drag-and-drop functionality, and one-click application of important settings, your rig will be up and running in no time.
Intuitive Graphical Fan Control
Fine-tune individual fans simply by dragging a curve with the mouse.
Improve DRAM performance with one click.
Aura On/Off Mode (Stealth)
Easily enable or disable Aura RGB lighting or every onboard LED, for a subdued aesthetic touch.
SATA port details that help easily recognize drives.
Little Things Make a Big Difference
We pay careful attention to all the little details that improve your overall experience, from utilizing exclusive codecs for pristine audio quality to intuitive RGB lighting controls for a customized look. Prime TRX40-Pro S provides the tools you need to personalize your build for a more enjoyable creation process.
Pre-Mounted I/O Shield
Set Up without Slip-Ups
Form meets function in the pre-mounted I/O shield that we pioneered with the ROG series motherboards. Now available on Prime TRX40-Pro S, this feature streamlines the installation process for budding builders and savvy enthusiasts alike.
The Chassis Reset Button – Reassigned
Flexkey, a front-panel header lets you customize the reset button on the front-panel of your chassis to provide quick access to our choice of Aura lighting controls, DriectKey or system reset.
Update Your BIOS Without CPU and DRAM
BIOS FlashBack is the simplest and safest (UEFI) BIOS update method. Simply drop the (UEFI) BIOS file onto a FAT32-formatted USB stick, plug it into the USB BIOS FlashBack port and press the button. Updates can even be performed without having memory or a CPU installed.
Realtek Codec and Unique Design Features for Pristine, Powerful Audio
Prime TRX40-Pro S utilizes a unique audio codec designed in close collaboration with Realtek — the Realtek S1220. It also features an unprecedented 120dB signal-to-noise ratio for the stereo line-out and a 108dB SNR for the line-in, providing pristine audio quality. Additionally, a new impedance-sensing circuit automatically adjusts the gain to ensure optimal volume range for your headphones.
DTS:X® Ultra adds a spatial audio feature to boost headphones and speakers for enhanced gaming, VR, and extended-reality experiences. DTS:X Ultra supports sound based on channels, scenes, and objects to allow for deeper sonic immersion in enabled content. It also provides post-processing enhancements and device-level tuning for DTS® codecs.
Flawless Audio that Immerses You in the Game
Reduces power-input noise to ensure consistent performance.
Separates analog/digital signal domains, significantly reducing multi-lateral interference.
Separate Layer for Left and Right Tracks
Ensures minimal crosstalk between audio paths.
Capable of driving high-impedance headphones, without rolling-off high or low frequencies.
Reduces start-up popping noise to all audio outputs.
Premium Japanese Capacitors
Premium parts provide an immersive sound signature, with exceptional fidelity.
Outshine the Competition
A well-tuned enthusiast system deserves a matching aesthetic. ASUS Aura offers full RGB lighting control with a variety of functional presets for the built-in RGB LEDs as well as strips and devices connected to the onboard RGB headers – and they can all be synced with an ever-growing portfolio of Aura-capable hardware.Learn more >
- Color Cycle
- Starry Night
- Music Effect
Addressable Gen 2 RGB Header
Prime TRX40-Pro S has two Addressable Gen 2 RGB Headers, which are now capable of detecting the number of LEDs on second-gen addressable RGB devices, allowing the software to automatically tailor lighting effects to specific devices. The new headers also offer backward-compatibility with existing Aura RGB gear.
Armoury Crate is a new software utility designed to give you centralized control of supported products. From a single intuitive interface, Armoury Crate allows you to easily customize RGB lighting and effects for every compatible device in your arsenal. The software also provides control of settings for ASUS products, including keyboard and mouse preferences. Armoury Crate even features dedicated product registration and highlight to help you stay in touch with the ASUS community.
Driver & Manual Download
The Power of AMD
AMD TRX40 Chipset
The AMD TRX40 chipset delivers outstanding overclocking capabilities for the latest AMD Socket sTRX4 3rd Gen Ryzen™ Threadripper™ series processors. It provides PCIe 4.0 support, 10 Gbps USB 3.2 Gen 2 ports, and eight SATA 6 Gbps ports for faster data retrieval.
Ready for AMD Socket sTRX4 3rd Gen Ryzen Threadripper
ASUS Prime TRX40-Pro S motherboard supports the latest 3rd Gen AMD Ryzen™ Threadripper™ series processors that boast up to 64 cores. It features quad-channel DDR4 memory, 64 lanes of PCI Express® 4.0, 16 GT/s transfer speed for Gen 4 M.2 SSDs, and built-in native USB 3.2 Gen 2 (10 Gbps) for superior performance.