Trusted by IT Experts. Built for Worry-Free Business.
Outstanding Value for business at any sizes
Engineered for the specific demands of small business, ASUS ExpertCenter D5 SFF is a desktop with AI-driven Microsoft Copilot that delivers powerful, trustworthy and expandable performance. Its modern, ultra-compact, and flexible design caters to diverse workspaces and usage scenarios — and allows businesses to take advantage of ASUS-exclusive small-business support services to minimize both downtime and total cost of ownership and maximize the value of your investment.
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Secure manageability
ExpertCenter D5 SFF prioritizes security through TPM 2.01, providing advanced protection with two options: a software-based firmware TPM solution running on the CPU; or discrete TPM (dTPM), a dedicated chip offering an additional layer of defense against sophisticated threats.
Efficient expandability
The perfect balance of performance and size with remarkable expandability that provides space for essential hardware to support diverse productivity needs.
Tool-free chassis
The redesigned tool-free chassis makes it easier to remove components by hand, simplifying routine servicing and making future upgrades a breeze.
Ultimate reliability
Built with industry-leading ASUS motherboards and tested to stringent ASUS and MIL-STD 810H US military standards2, minimizing risk of damage and maximizing longevity.
Exceptional performance, whatever the task
To make light work of all your business tasks, ExpertCenter D5 SFF is powered by the latest Intel® Core™ 14th gen processors with up to 64 GB DDR5 RAM. An NVIDIA® discrete GPU is an option for those requiring advanced graphics performance for demanding visual tasks.
Microsoft Copilot
AI-powered Microsoft Copilot4 in Windows with commercial data protection is your Al assistant at work. Supercharge your productivity and achieve more with less time and effort using Copilot AI. Experience your everyday Al companion now with the dedicated Copilot key. Just one click for endless exploration.
Maximize your workspace
ExpertCenter D5 SFF desktop with AI-enhanced Microsoft Copilot is up to 10%5 smaller than previous-generation models, making it even more compact — help to maximize your office workspace. And its sleek and elegant design gives your business a truly professional look — ready to work in style.
Hassle-free maintenance and upgrades
ExpertCenter D5 SFF has a redesigned tool-free chassis. The removable HDD cage offers more accessibility to the motherboard, and the ODD also comes off easily, making component upgrades and routine servicing easy.
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Power to do more
To adapt seamlessly to your business workflow, ExpertCenter D5 SFF features a full array of expansion capabilities, including flexible back I/O ports, storage, graphics and WiFi. It’s easy to configure for all your current and future demands.
Less heat, more productivity
To ensure stable performance, ExpertCenter D5 SFF employs an innovative multi-channel cooling system. This compact workhorse also incorporates the exclusive MyASUS app to optimize the operation of the CPU and system fans, automatically moderating the speeds and switching them off completely when possible, striking the perfect balance between maximum performance and minimum noise.
AI noise-canceling audio technology for business
To level up professional conferencing, ExpertCenter D5 SFF desktop has two-way AI noise-canceling technology6 that employs sophisticated machine-learning techniques. The technology includes both an upstream function to filter noise around the speaker, and a downstream function to eliminate noise from the person at the other end of the conversation. Try the demo to experience the amazing difference that ASUS two-way AI noise-canceling technology can make.
Turn on your device’s audio and press play to experience AI noise-canceling technology.
Committed to creating a sustainable future, ASUS ensures all its products are compliant with environmental requirements at all stages of their product life cycles. The ExpertCenter D5 SFF is registered as EPEAT Gold7, and is also ENERGY STAR® 8.0-certified to reduce long-term costs with its energy-efficient design.
ASUS Endpoint Management Services (AEMS)8 supports clients’ business success with reliable devices and services. Our solutions encompass on-premises and cloud-based management, empowering IT managers to consolidate systems, deploy new software and hardware, streamline processes and offer a seamless management experience.
ASUS Pre-Deployment Services (APDS)8 streamline operations to ensure lightning-fast deployment of pre-configured PCs, ready for immediate use on day one. Carefully tailored to your unique needs, our user-friendly approach guarantees a hassle-free experience that will transform the way you deploy and manage your IT infrastructure.
Expert-series PCs are solidly-built and tested to the most demanding industry requirements, including MIL-STD 810H US military standards and stringent ASUS in-house testing. The inevitable minor shocks and everyday workplace accidents won’t jeopardize your precious data2.
ExpertCenter desktops use ASUS motherboards — the world’s #1 motherboard brand9 — which are renowned for offering comprehensive system protection to safeguard hardware, 24/7 stability through extensive testing, and consistent performance.
ExpertCenter desktops are engineered with 100% solid capacitors for better performance and longevity, with a lifespan that’s up to 2x greater than traditional capacitors with the CPU under full load and 6x longer during everyday use5. This maximizes your investment and minimizes the need for maintenance — all contributing to a lower total cost of ownership (TCO).
Ready for the business world
A full array of I/O ports is ready to connect ExpertCenter D5 SFF to a wide range of business peripherals. It has four front-mounted USB ports for quick and easy access and flexible serial port on chassis leave more PCI Express® slots available for additional upgrades and an optional SD card reader for easy transactions, data transfer, or other business-related tasks.
HDMI port 1.4
VGA port
Optional port (include HDMI 2.1 TMDS / DP 1.4 / VGA)
USB 3.2 Gen 1 Type-A x 2
USB 2.0 Type-A x 2 (support USB keyboard power-on function)
1Gb LAN port w/ LED indicator
Microphone port
Line-out port
Line-in port
Serial port (optional)
HDD LED indicator
System status & LAN port indicator
Optical disc drive bay (optional)
Headphone port
Audio combo jack
USB 2.0 Type-A x 2
USB 3.2 Gen 2 Type-A x 2
SD card reader (optional)
- Actual product appearances may vary, and the images displayed are for illustrative purposes only; please refer to product descriptions for accurate information.
- Trusted Platform Module (TPM) is optional.
- The testing regime includes the requirements of both military-grade standards and ASUS quality tests and varies depending on device. MIL-STD-810H testing is conducted on selected ASUS products only. Note that the MIL-STD-810H testing helps to ensure the quality of ASUS products but does not indicate a particular fitness for military use. The test is performed under laboratory conditions. Any damage caused by attempts to replicate these test conditions would be considered accidental and would not be covered by the standard ASUS warranty. Additional coverage is available with ASUS Premium Care.
- Please note that ExpertCenter D5 SFF includes up to 2 x 1 TB M.2 SSD, and up to 1 x 2 TB 3.5” HDD, for total storage capacity of up to 4 TB.
- a) Screen simulated, subject to change. Feature availability and rollout timing varies by market and device.
b) Copilot in Windows (in preview) is rolling out gradually within the latest update to Windows 11 in select global markets. Timing of availability varies by device and market. Learn more: https://www.microsoft.com/en-us/windows/copilot-ai-features?r=1#faq
c) Copilot with commercial data protection requires Microsoft 365 E3, E5, Business Standard, Business Premium or A3 or A5 for faculty, or accessed using Microsoft Entra ID. - Based on ASUS internal testing and measurements. Unless otherwise stated, all performance claims are based on theoretical performance. Actual figures may vary in real-world situations.
- AI noise-canceling audio technology only applies when connected to external mics.
- D501SERS refers to the SKUs of D501SER with Energy Star and EPEAT certifications.
- ASUS Endpoint Management Service (AEMS) and ASUS Pre-Deployment Service (APDS) are optional, and their availability varies according to country. Please check with your local ASUS retailer for details.
- ASUS secured the #1 spot for motherboard market share as of 2017, with DigiTimes reporting that the Taiwanese PC component giant owns 45% of the motherboard market.
