Pro WS C621-64L SAGE/10G

Intel LGA 3647 CEB workstation motherboard with dual Intel 10G LAN and support for 4 GPUs, 12 DIMMs, 10 SATAs, M.2, USB 3.2 Gen 2 and ASUS Control Center
  • Single-socket motherboard is designed for Intel® Xeon® W-3200 processors and Intel Xeon Scalable processors
  • Dual Intel® 10G LAN offers increased data throughput and improved efficiency, making it ideal for large file transfers and backup
  • Fits up to four double-decked actively or passively cooled graphics cards with true PCIe® Gen 3 x16 link bandwidth, and supports NVIDIA® Tesla and Quadro®
  • Supports up to 12 DIMMs for up to 1.5 TBof memory with Error-correcting code (ECC) for increased accuracy in designsand simulations and system reliability
  • Ultra-efficient VRM heatsink: Metal-fin-array design maximizes surface area for heat dissipation to enable unthrottled performance
  • Complete IT infrastructure management with ASMB9 out-of-band remote management and in-band ASUS Control Center software
  • Next-gen transfer speeds with an up to 32 Gbps M.2, plus an up to 10 Gbps USB 3.2 Gen 2 Type-A and Type-C™
Pro WS C621-64L SAGE/10G

ASUS Pro Workstation motherboards are designed for professionals working in AI, deep learning, animation, 3D rendering or media production. Featuring expandable graphics, extensive storage, impressive connectivity and exceptional overall performance and reliability, Pro Workstation motherboards are the ideal solution for creative professionals. Each motherboard includes centralized management software with support for out-of-band management, so they're also an efficient and cost-effective option for IT administrators.

1 2 x USB3.2 Gen2 ports
(Type-A & Type-C)

2 2 x 10GbE LAN port
(Intel X550)

3 USB BIOS Flash-back

4 4 x USB3.2 Gen1 ports

5 5 x Audio jacks
+ 1 x SPDIF/out
Support 7.1-channel


7 Intel LGA 3647 socket support
- Intel Xeon W-3200 processors
- Intel Xeon scalable processors

8 12 x DIMM slots
(DDR4 2933 RDIMM)
Support 6-channel, 2DPC

9 1 x USB 3.2 Gen 1 header

10 10 x SATA 6Gbps ports

Total 5 PCIe slots
  • Slot-7 : PCIe x16 slot (Gen3 x16 link)
  • Slot-5 : PCIe x16 slot (Gen3 x16 link)
  • Slot-4 : PCIe x16 slot (Gen3 x4 link)
  • Slot-3 : PCIe x16 slot (Gen3 x16 link)
  • Slot-1 : PCIe x16 slot (Gen3 x16 link)
    * Only Intel Xeon W-3200 processors support 64 PCIe lanes

12 Intel C621 PCH

13 1 x M.2 connector
(up to 22110 type)

Architecture, Engineering and Construction

Media and Entertainment

Artificial Intelligence

Breakthrough Performance

Breakthrough performance in a single-socket solution

Built for advanced workstation professionals, Pro WS C621-64L SAGE/10G is powered by the latest Intel® Xeon® W-3200 processors that support up to 28 cores, 56 threads and 64 PCIe 3.0 in a single socket. Designed for faster visualizations, simulations and rendering capabilities across demanding applications of all types, Pro WS C621-64L SAGE/10G also supports Intel® Xeon® Scalable processors, which utilize the same six-channel LGA3647 socket as the Intel Xeon® W-3200 processors.

Dual onboard 10G LAN

Featuring dual onboard 10G LAN ported by the cutting-edge Intel® X550 10GBASE-T Ethernet Controller, Pro WS C621-64L SAGE/10G provides server-grade connectivity and supports high-density, high-bandwidth, low-latency access-layer networks to ensure faster transfers of large-size files used in data-intensive applications.

Multi-GPU support

Four GPUs support, faster bandwidth

Pro WS C621-64L SAGE/10G fits up to four double-decked actively or passively cooled graphics cards, which each support PCIe Gen 3 x16 link bandwidth to ensure fast and fluid animations and model rendering. It also supports the latest NVIDIA® Tesla® and Quadro® graphics cards to deliver the horsepower needed to run design, modeling, medical research, and processing-intensive simulations and rendering applications.

Trusted reliability

Make your memory faster and reliable

Along with 12 DIMM for up to 1.5 TB of memory, Pro WS C621-64L SAGE/10G supports Error-correcting code (ECC) to eliminate application or system crashes by automatically detecting and repairing single-bit memory errors.

IT management

Comprehensive IT infrastructure management

Pro WS C621-64L SAGE/10G features an embedded ASMB9-iKVM and ASUS Control Center software to provide comprehensive out-of-band and in-band management features for enterprise and small or mid-size businesses.

The embedded ASMB9 iKVM supports remote BIOS updates, fan control, standalone KVMs, video recording, and BSOD capture, providing around-the-clock remote monitoring and diagnostics — even if the operating system is down or offline.

The ASUS Control Center (ACC) is a centralized and integrated IT management platform for monitoring and controlling ASUS commercial products, including servers, workstations and digital signage. ACC enables remote BIOS updates, monitoring of multiple systems via mobile devices, and one-click software updates and dispatching, allowing easier server management for any IT infrastructure.

Ultra-efficient cooling

Multiple Ultra-efficient heatsinks

A header to keep ahead

Pro WS C621-64L SAGE/10G features a thoughtful thermal design to ensure maximum performance with no CPU throttling. Its ultra-efficient VRM heatsink with a metal fin array maximizes surface area for heat dissipation, and its heatsinks and a connecting heat-pipe that's situated in the direct path of airflow combine to ensure optimal cooling performance — even under the most demanding workloads.

M.2 heatsink

Keep your SSD cooler

Pro WS C621-64L SAGE/10G features an ultra-efficient heatsink to reduce M.2 SSD temperatures for optimal storage performance and improved SSD longevity.

Intel VROC

Combining the performance and flexibility that designers want and need, Pro WS C621-64L SAGE/10G supports an ASUS NVMe® riser card to expand to up to four NVMe SSDs, and it utilizes Intel® Virtual RAID on CPU (VROC) to directly attach NVMe SSDs to the CPU PCIe lanes to unleash NVMe RAID performance.

* Intel® VROC is supported via RSTe, VROC_HW_Key are to be purchased separately. NVMe RAID type and function will depend on Intel® VROC_HW_ key installed.


Protect your graphics card investment

SafeSlot is the PCIe slot reinvented by ASUS and engineered to provide superior retention and shearing resistance. Manufactured in a single step using an insert-molding process, SafeSlot integrates the slot with fortifying metal for an inherently stronger slot, which is then firmly anchored to the PCB through additional solder points.

Ready for Intel® Xeon® W-3200 Processors The Intel® Xeon® W-3200 processors are purpose built and optimized for advanced workstation professionals in a single-socket solution. These processors are designed for heavily and lightly threaded, I/O-intensive workloads across architecture, engineering, and construction (AEC), media and entertainment (M&E), artificial intelligence (AI), oil & gas, and data sciences.

Ready for Intel® Xeon® Scalable Processors Drive actionable insight, count on hardware-based security, and deploy dynamic service delivery with Intel® Xeon® Scalable processors. Support your hybrid cloud infrastructure and most demanding applications – including in-memory analytics, artificial intelligence, autonomous driving, high performance computing (HPC), and network transformation.

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