Intel® W680 (LGA 1700) ATX motherboard, PCIe® 5.0, DDR5, dual Intel® 2.5 Gb Ethernet, three PCIe 4.0 M.2 slots, USB 3.2 Gen 2x2 front panel connector, SlimSAS, SATA 6 Gbps, HDMI®, DisplayPort and VGA
  • Intel® LGA 1700 socket: Ready for 14th, 13th and 12th Gen Intel® Core™ Processors
  • Enhanced power solution: DrMOS, ProCool connector, alloy chokes and durable capacitors for stable power delivery
  • Next-gen connectivity: Dual PCIe 5.0 SafeSlots, dual PCIe 3.0 slots, 3 x M.2 PCIe 4.0, SlimSAS, dual Intel® 2.5Gb Ethernet, front panel USB 3.2 Gen2x2 Type-C®, Thunderbolt™ 4 header support, TPM header, LPT header
  • Comprehensive cooling: Large VRM heatsink, M.2 heatsinks, hybrid fan headers and Fan Xpert 4
  • Advanced security management: USB port management, software blacklisting and Regedit on/off controls via ASUS Control Center Express
  • Trusted stability: Tested for 24/7 operation, validated for extensive compatibility and equipped with SafeSlot and SafeDIMM for enhanced durability
Pro WS W680-ACE

Pro logo

ASUS Pro Workstation motherboards are designed for professionals in AI training, deep learning, animation, 3D rendering or media production. Featuring expandable graphics, extensive storage, impressive connectivity and exceptional overall performance and reliability, Pro Workstation motherboards are the ideal solution for creative professionals. Each motherboard includes centralized management software, so they're also an efficient and cost-effective option for IT administrators.

Pro WS W680-ACE motherboard performance features

1 MOS-W Heatsink

2 1 x PCIe 3.0 x1

3 2 x PCIe 5.0 x16
- ASUS SafeSlot

4 2 x PCIe 3.0 x16 (x4 mode)

5 LPT Header

6 MOS-N Heatsink

7 4 DIMM, Max 192GB, DDR5 4800 ECC and non-ECC U-DIMM Support ASUS SafeDimm

8 Intel® Socket LGA1700 for 14th, 13th & 12th Gen Intel® Core™ Processors, Pentium® Gold and Celeron® Processors

9 USB 3.2 Gen 1 header

10 USB 3.2 Gen 2x2 Type-C® Connector

11 3 x M.2 PCIe 4.0 x4 mode

12 1 x 6-pin PCIe Power connector

13 1 x SlimSAS
supports PCIe 4.0 / SATA mode

14 Intel® W680 Chipset

15 PCH Heatsink

16 4 x SATA 3.0 ports

17 BMC Header

18 2 x USB 2.0 headers

19 Thunderbolt Header

Video Editing

3D CAD and Rendering

IT Management

Ultra Powerful Back IO

The motherboard comes with four USB 3.2 Gen 1 type connector, one reversible USB Type-C connector and front-panel connector to support additional USB expansions.

I/O port connectivity I/O port connectivity


2 x USB 2.0

Intel® 2.5GbE

8-CH Audio



4 x USB 3.2 Gen 1

2 x USB 3.2 Gen 2
(1 x Type-A, 1 x Type-C)

BIOS FlashbackTM button

ECC Memory Support

ECC Memory Support

Designed for creative professionals who require outstanding performance, reliability and enhanced security, ASUS Pro WS W680-ACE motherboard is powered by the 14th, 13th and 12th Gen Intel® Core™ processors for always-on usage scenarios and supports ECC memory to automatically detect and correct data corruption, reducing the chance of system crashes to ensure workstation stability.

ECC memory support layout highlight
Dual 2.5G Ethernet

Dual 2.5G Ethernet

Boosted connectivity with dual onboard Ethernet ports. Intel 2.5G Ethernet upgrades your traditional LAN connection with an up to 2.5X bandwidth improvement. Using your existing Ethernet cable, you can experience faster file transfers and immediately stream high-resolution videos.

Intel dual Ethernet icon
Dual 2.5G Ethernet layout highlight
ASUS Control Center Express

ASUS Control Center Express

The best business performance requires smart IT management. ASUS Control Center Express is an intuitive and secure software designed to simplify IT operations and improve workload productivity by providing comprehensive control of all the systems in your organization. Plus, ASUS Control Center Express is compatible with over 100 ASUS motherboards to give you more upgrade flexibility and less compatibility issues.

less than 5 mins faster installationFaster Installation
3 steps easier migrationEasier Migration
100 more ASUS motherboards compatibleASUS Motherboards Compatible
ASUS Control Center Express dashboard UI
1 ASUS Control Center Express Floor plan UI
ASUS Control Center Express hardware list UI
Multi-GPU Support

Multi-GPU Support

Two PCIe 5.0 x16 slots provide flexible system configurability and expandability — including support for NVIDIA® Quadro® — for enhanced performance in modelling, simulation, and rendering applications.

Multi-GPU Support layout
Multi-GPU Support layout
Tune it your way
Triple M.2

Triple M.2 Slots

Triple M.2 slots support PCIe 4.0, offering up to 64 Gbps data-transfer speeds and flexible M.2 interfaces. The RAID 0/1/5/10 configuration are available for the data protection and increases fault tolerance to the entire system, higher storage capacity and better SSD performance.

Triple M.2 Slots layout

Thermal Solution

VRM heatsink

A large, high-mass heatsink with extensive surface that covers the VRM and choke areas improves heat dissipation.

PCH heatsink

An expanded surface area for the chipset cooler maximizes performance and heat dissipation.

M.2 heatsink

M.2 slot has a dedicated heatsink keep the M.2 SSD at optimum operating temperature to ensure consistent performance and reliability.

Thermal Solution layout


The innovative Q-Latch makes it easy to install or remove an M.2 SSD without the need for specific tools. The design employs a simple locking mechanism to secure the drive and neatly eliminate traditional screws.

Q-Latch M.2 layout

SafeSlot & SafeDIMM

PCIe 5.0 is 2x faster than PCIe 4.0, so we adapted our SMT manufacturing process for the faster SafeSlot, to ensure the highest data speeds. SafeSlot is a reinforced metal sheath added to a PCIe slot to keep a card firmly installed. Meanwhile, strong ASUS SafeDIMM sheathes support and protect memory modules on select ASUS motherboards, empowering you to insert your modules with speed, accuracy and confidence.

SafeSlot & SafeDIMM layout
24/7 Dependability

24/7 Dependability

Optimized for 24/7 operation, Pro WS W680-ACE motherboard is tested to work in temperatures of up to 45°C and 80% humidity, ensuring it can handle diverse operating environments.

24/7 Dependability

Solid Compatibility Validation

ASUS Pro WS W680-ACE motherboard has been extensively tested for compatibility with over 1,000 components and devices. Each new ASUS motherboard model undergoes a minimum of 8,000 hours of strict tests so that you can be 100% confident it is suitable for all environments and applications.

520 more DDR5 compatibility

DDR5 compatibility

Industry-leading DDR5 memory compatibility for best flexibility and reassurance.

520 more DDR5 compatibility
1000 more compatible devices

compatible devices

Compatibility with a range of CPUs, memory modules, graphics cards and more.

1000 more compatible devices
8000 more validation hours

validation hours

Extensive testing with latest components for enhanced reliability, compatibility and safety.

8000 more validation hours
Server-grade IT management
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